In the world of Destiny 2, it’s hardly unexpected that high Damage Per Second (DPS) weapons are in great demand. When tackling bosses, these powerful weapons become essential for players. You see, most game bosses have brief moments of vulnerability, and therefore, fireteams require guns capable of dishing out massive damage within those short timeframes.
Choosing the optimal weapon to use against various bosses in Destiny 2 can be quite perplexing, especially for novice players. In this guide, we’ll discuss some effective weapons that players might find useful when confronting the diverse array of bosses, presented without any specific ranking.
Outbreak Perfected
Best Primary for Boss Fights
In most cases, standard weapons aren’t ideal for taking down bosses, but Outbreak Perfected stands out as an exception. This weapon can swiftly deplete boss health bars with its nanite swarms. If every member of the fireteam wields this weapon, the rate at which nanite swarms are generated increases dramatically, leading to a substantial boost in overall DPS.
In a nutshell, Outbreak Perfected may not be the best at shattering boss records, but it’s an excellent standby weapon during challenging boss fights like that of Oryx in King’s Fall. If your team is running low on Heavy and Special Ammo, Outbreak Perfected can surely lend a helping hand.
Gjallarhorn
Best Weapon for Rocket Launcher Strats

The Gjallarhorn isn’t great for dealing boss damage directly, but it excels in enhancing the performance of other rocket launchers in a team. When equipped, it boosts the rockets of fellow players, causing them to explode into swarms of homing sub-munitions upon impact. This is particularly beneficial for Legendary Rocket Launchers like Hezen Vengeance, as they can be rolled with both Envious Arsenal and Bait and Switch.
In summary, Gjallarhorn is an exceptional weapon, however, it’s best utilized if only one team member carries it. Use it as a supportive tool when battling bosses, but against regular enemies, feel at liberty to unleash its power whenever desired.
VS Chill Inhibitor
Max Damage Mag Dumps

Similar to the Hezen Vengeance, the VS Chill Inhibitor can work effectively with the Envious Arsenal/Bait and Switch optimal setup, making these two weapons quite versatile and potentially swapable. Both are Legendary weapons, leaving an open Exotic slot for your team’s remaining equipment needs.
When it comes to legendary weapons, the VS Chill Inhibitor isn’t the only grenade launcher worth considering by players. If your power weapon is equipped with a perk like Bait and Switch or another comparable damage-enhancing attribute, it tends to perform effectively against most bosses in general.
Izanagi’s Burden
Ol’ Reliable

The trustworthy weapon known as Izanagi’s Burden is particularly effective against bosses, especially for those employing a weapon-swap strategy during damage stages. It harmonizes flawlessly with the earlier mentioned Chill Inhibitor and Hezen Vengeance, and it will function satisfactorily with other weapons that leverage quick swaps, as long as players can seamlessly incorporate Izanagi’s special reload into their rotation of weapon changes.
In most cases, sniper rifles work effectively against static targets such as the Templar within the Vault of Glass. However, remember to factor in the recoil (or ‘flinch’) when employing these rifles during the damage stages to ensure accurate shots.
Thunderlord
Hail to the King

If you prefer a weapon that doesn’t require much fine-tuning, the Thunderlord Exotic Machine Gun is a fantastic choice. Not only does it increase its firing speed when the trigger is held down, but it also summons lightning bolts onto your target. Additionally, it works particularly well with Bolt Charge Titan builds, enhancing the number of lightning strikes and leading to impressive damage output.
Thunderlord is an excellent weapon for tackling bosses that demand frequent movement or frequent adjustments in aim. If the boss you’re farming proves difficult to target, then Thunderlord could be a reliable backup choice.
Queenbreaker
Point, Click, Profit

Just like Thunderlord, Queenbreaker excels at quick and potent boss elimination through aim-and-fire mechanics. It dishes out significant damage when fired in triple-shot bursts, although it demands players to consistently land Precision Hits for maximum impact. However, it’s a fairly lenient weapon to manage, offering some leeway for inaccuracies.
In today’s gameplay, Linear Fusion Rifles aren’t typically top-tier for boss damage. However, if this season includes mods such as Particle Deconstruction, these rifles could prove useful in some capacity.
Falling Guillotine
Spin to Win

In some challenging boss encounters, a sword can prove more effective than a gun. Among legendary swords, the BRAVE version of the Falling Guillotine stands out as an exceptional choice. Any sword with Relentless Strikes or Whirlwind Blade is solid, but Vortex Frame swords like the Falling Guillotine are particularly powerful and dependable for most boss battles.
One great aspect of this weapon is its ease of acquisition through the Onslaught activity. To succeed, you’ll want a robust setup capable of repelling waves of enemies and a dose of persistence. With some good fortune and dedication, you’ll likely secure an ideal Falling Guillotine for your boss-fighting endeavors.
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2025-05-23 10:48