Best Vex Siren Build in Borderlands 4 (Incarnate Tree)

In the game Borderlands 4, the character Vex the Siren boasts some incredibly powerful, albeit flawed, build options. One particularly overpowered (OP) build for a Siren in this game relies on the Incarnate Skill from the green skill tree. To create an extremely strong Siren in Borderlands 4, players should focus on acquiring and upgrading these specific skills and equipment items. This build is centered around Vex as a formidable source of true damage, capable of effortlessly dismantling bosses and high-level enemies, thanks to multiple layers of damage amplifiers from Critical Hits and Kinetic Damage weapons, pushing well into Ultimate Vault Hunter Rank 5.

Best Skills for Incarnate Vex

Skill Description Why It’s Useful
Leeching Attunement (1/5) Attunement Skill. While Vex is Attuned to Kinetic, she gains Lifesteal and increased Reload Speed. These effects persist for a Duration after Attunement is switched. This makes Kinetic weapons more effective by allowing Lifesteal and Reload Speed bonuses.
Grave Sights (5/5) Kill Skill. Vex gains increased Critical Hit Damage and Gun Handling. This allows Critical Hit Damage to stack on kills, providing an increase to damage and handling.
Bloodletter (5/5) Gun and Skill Critical Hits have a chance to apply Bleed, causing Kinetic Status Effect Damage over time for a Duration. Bleed is affected by Status Effect Application Chance, and is itself considered a Status Effect. A Critical Hit has a chance to apply Bleed, which causes more Kinetic Damage over time, with a max stack of 20, providing an immense amount of damage.
Grave Implements (5/5) Kill Skill. Vex and her Minion(s) gain increased Gun Damage for a Duration. A +20% increase to Gun Damage with a max of 3 stacks will help build Vex’s damage numbers.
Material Components (4/5) MAYBE Vex gains increased Kinetic Damage and Kinetic Status Effect Damage. More Kinetic Damage is great, but Kinetic Status Effect Damage will boost Bleed even more.
Grave Power (3/3) Vex’s Kill Skill gain increased Max Stacks. More Max Stacks, means more overall damage on Kill Skills, almost doubling some skills.
Witchy Trigger Finger (Augment) Dealing Damage with Eldritch Blast or Phase Explosion will fully Refill Ammo of Vex’s current Gun, and grants a stack of Witchy Trigger Finger, increasing Gun Damage for a Duration. Stacks of Witchy Trigger Finger persist even after Incarnate ends. Using the Action Skill will not only deal immense damage and fully heal Vex, but it will now reload her weapon and grant extra Gun Damage when the Action Skill causes any damage.
Drink Full (5/5) Whenever Vex deals Gun Damage, she gains a Stack of Drink Full, increasing her Fire Rate. Stacks of Drink Full are lost if a new Stack has not been gained for a Duration. Increases Fire Rate with a Max Stack of 50, meaning a 30% increase to Fire Rate.
Mortal Terror (5/5) Chance to Activate Kill Skills when Critically Hitting enemies. Shooting enemies in their Critical Hit spots means that you can gain Kill Skill Stacks without killing enemies, perfect for boss fights with little ads.
Vibe Check (Capstone) Eldritch Blast is now a Charge Skill (3) Activating Eldritch Blast consumes all Charges to Ricochet on hitting an enemy. Will Ricochet once for each Charge consumed. Eldritch Blast’s Cooldown reduction from Gun Damage is doubled Vex’s Action Skill recovers faster with Gun Damage, and it can now be fired at enemies from range.
Strike Me Down (1/1) Whenever Vex would enter Fight For Your Life, she immediately gets a Second Wind, becomes Invisible for a Duration, and causes a Phase Explosion. This is a get out of jail free card every 120 seconds, and the damage from Phase Explosion is great.
Sanguine Fiends (1/5) Kill Skill. Vex and her Minion(s) restore Health. Killing enemies, or activating a Kill Skill from Mortal Terror, immediately regains a portion of HP.
Cold Iron (5/5) Vex gains increased Gun Damage. The more Gun Damage, the merrier.
Portents of Suffering (3/5) Vex and her Minion(s) gain increased Status Effect Damage. More Status Effect Damage directly impacts the Bleed damage of Kinetic Damage for even more powerful shots.
Grave Assault (1/5) Kill Skill. Vex and her Minion(s) gain increased Fire Rate for a Duration. This is an additional 9% to Fire Rate thanks to Grave Power, meaning players will nearly double their total Fire Rate.
Grave Fiends (5/5) Kill Skill. Vex and her Minion(s) deal increased Damage. More Damage Dealt per Kill Skill, and with Grave Power, that’s a total of +70%.

In this Vex Incarnate setup, players will primarily focus on the Vexcalation skill tree, with a key emphasis on Kill Skills for boosted Fire Rate and Gun Damage. However, the cornerstone of this build is undeniably the Bloodletter ability. This skill offers a chance to inflict Bleed on critical hits, adding extra Kinetic Status Effect Damage. The critical hit damage can accumulate exponentially as long as the Bleed effect is continuously applied.

To execute this strategy effectively, use a Throwing Knife Ordnance equipped with Penetrator Augment, making any point on the target a critical hit zone. Once the ammo is depleted on an enemy, unload it and let the Bleed accumulate. Afterward, hurl the Knife Ordnance again to reapply more critical hit damage. This cycle can be repeated across multiple enemies to swiftly defeat bosses and common foes, even without the Throwing Knife itself.

Best Weapons and Gear for Incarnate Vex

Vex’s Incarnate build primarily emphasizes two key aspects: Kinetic Energy weapons and Throwing Knife ammunition. While players are free to select their preferred primary weapons, we suggest obtaining the Axemaul from The Toil of Spoiling Vis Auger Mine in Carcadia District within Dominion. This boss has a chance to drop Armored Bod, an exceptional Legendary Shotgun that acts as a Shotgun, Assault Rifle, Sniper Rifle, Pistol, and SMG. The versatility of this weapon complements Vex’s damage skills perfectly.

In the world of Ordnance, having a Throwing Knife becomes indispensable for boosting this particular build to an overpowered (OP) level. However, not every Throwing Knife is suitable; you should specifically search for one equipped with the Penetrator Augment. This unique feature ensures that any strike on the target is a critical hit, regardless of your aiming point. The Penetrator Augment is crucial to making the build effective, but the Damage AMP Payload can also be beneficial as it amplifies the damage inflicted upon the target.

To optimize your Repkits and Class Modifications, aim for those that offer substantial stat boosts, such as increased health, Elemental Affinity, or damage bonuses. When selecting Shields, choose the ones you’re most comfortable with. For Enhancements, prioritize upgrades that enhance Critical Damage and Weapon Damage.

Best Specializations for Incarnate Vex

Specialization Perk
Brute (20) Riddle You This
Sharpshooter (10) In The Zone
Killer (10+) Contamination Compounding Afflictions

Vex Incarnate’s primary areas of expertise are Brute and Sharpshooter. To maximize combat effectiveness, players should focus on raising Brute to level 20. This level-up increases overall Gun Damage and introduces a crucial skill called “Riddle You This.” Using this ability increases the Gun Damage based on the amount of damage dealt, with up to 50 stacks granting an additional 50% damage boost. Once Brute is maxed out, players should invest in Sharpshooter for faster reload speed and improved accuracy, but only enough to unlock “In The Zone.” This skill increases both Gun Damage and Critical Hit Damage while aiming. The remaining points should be allocated primarily into the Killer specialization for increased Critical Hit Damage and Status Effect Damage. Additionally, pick up Contamination to enhance the chance of applying status effects on critical hits, and Compounding Afflictions to amplify damage based on the number of status effects applied.

Best Firmware for Incarnate Vex

Firmware Bonuses Slots
Deadeye Gun Accuracy is increased by +30% Gun Critical Damage is increased by +25% Every Critical Hit grants 15% Critical Damage per Stack (for a Maximum 5 Stacks) for 10s 3
Oscar Mike Gun Reload Speed is increased by +10% Gun Damage is increased by up to +20% based on the emptiness of your Gun’s Magazine 2

In this construction, the vital software required is Deadeye, especially with all three components installed. This upgrade increases both Gun Accuracy and Gun Critical Damage significantly, enhancing overall damage output. Additionally, it raises damage from Critical Hits. For additional benefits, you can select Oscar Mike at your discretion; we chose it to boost Gun Damage and Gun Reload Speed for high-intensity scenarios.

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2025-09-14 00:05