Resident Evil 4 Remake: Best Challenge Runs To Try

Key Takeaways

Custom challenge runs in
Resident Evil 4 Remake
offer players exciting new ways to experience the familiar game.
Players can create unique challenges like avoiding the use of storage, charms, or knives, or sticking to explosives only to keep the gameplay fresh.
Expert players can push their skills to the limit with more intense runs, such as the No Kill challenge or the Perfect Accuracy run.

As a seasoned Resident Evil 4 Remake survivor with countless hours under my belt, I can confidently say that these custom challenge runs are not for the faint-hearted. They push your skills to the limit and test your resolve like no other.

In a refreshing reinterpretation, Resident Evil 4 Remake seamlessly combines action and terror within the horror genre, empowering players to combat the chilling encounters using an array of resources to surmount any challenge. However, even after multiple playthroughs, veteran gamers who have conquered the game as Leon Kennedy across all difficulty levels might find the traditional approach somewhat repetitive. This is where specialized playthroughs known as “challenge runs” prove beneficial, introducing innovative perspectives and sustaining the adrenaline rush.

In the Resident Evil 4 Remake, there are pre-set challenges for gamers to conquer right off the bat. These range from Silent Stranger (completing the game without interacting with the merchant), Frugalist (avoiding all healing items), Minimalist (finishing the game with just knives and pistols), and Sprinter (beating the game in less than 8 hours). But what’s truly exciting is that players can devise their own custom scenarios, making each fresh playthrough distinct, enjoyable, and captivating. Here are some intriguing and fun challenge runs to attempt in Resident Evil 4 Remake.

1 Weapon Of Choice Run

Use Only One Firearm Throughout The Entire Playthrough

Resident Evil 4 Remake: Best Challenge Runs To Try

The Resident Evil 4 Remake features a variety of weapons such as handguns, shotguns, rifles, and submachine guns. An intriguing challenge in this game is sticking with a single weapon throughout the entire gameplay, without ever swapping to another firearm.

Players have an optional challenge: they can decide not to enhance their weapon, or alternatively, engage in the game using their preferred fully-enhanced firearm. Regardless of their choice, they should anticipate challenging portions because much of the game is constructed assuming that players will swap weapons for optimal performance.

2 No Knife Run

Refrain From Using Any Knives

In the world of Resident Evil 4 Remake, I can’t imagine surviving without my trusty knife. It’s not just a weapon; it’s an essential tool that lets me perform silent takedowns, dish out damage in fights, and even shield myself from deadly enemy attacks. So, if you think you’ve got the guts for it, give the No Knife challenge a try – it’s designed for the fearless!

As a devoted player, I can say that while knives are essential in certain pivotal scenes like the Krauser fights, the game allows me to largely bypass combat or non-upgradable kitchen knives in other parts of the game. Instead, I can rely exclusively on firearms for dealing damage and use dodges to steer clear of attacks.

3 Natural Healer Run

Only Eggs, Fish, Or Snakes Allowed For Healing

The Natural Healer mission presents players with a distinct survival test, differing from the challenging Frugalist run. In this scenario, Leon can’t utilize herbs or healing sprays to recover; instead, he must depend entirely on nature’s offerings: eggs, fish, and snakes (vipers). This is indeed an intriguing test of our agent’s carnivorous resourcefulness.

During the initial phase of this game, it may prove challenging since farming fish and snakes isn’t as straightforward. However, as time progresses, the task becomes less demanding. For those seeking an increased level of challenge, refraining from upgrading the attaché case could be beneficial, as it restricts the number of healing items you can carry later on.

4 Gun Game Run

Use Only One Weapon Per Chapter And Then Sell It

Drawing inspiration from the thrilling Gun Game mode in Call of Duty: Black Ops, this endeavor provides a novel and invigorating approach to playing the Resident Evil 4 Remake. The guidelines are straightforward: participants can utilize only one weapon per chapter. At the start of each new chapter, they must dispose of that weapon and select a new one. Given that the game comprises 16 chapters and 16 weapons (discounting deluxe or bonus weapons), this run offers a seamless fit for the challenge.

One engaging aspect of playing Gun Game is its unforeseeable nature, as it introduces surprising hurdles depending on the firearm each player is compelled to employ. This makes every weapon’s distinct advantages apparent, ensuring that the gaming experience remains innovative and thrilling across all stages.

5 No Storage Run

Do Not Interact With The Storage Box Throughout The Playthrough

As a devoted fan, I’d say running a No Storage playthrough in the Resident Evil 4 Remake presents an engaging challenge. Contrary to its popularity in the remakes of Resident Evil 2 and Resident Evil 3, RE4 Remake comes with a more spacious inventory from the get-go. But that doesn’t mean skipping the storage box (found at Typewriters) eliminates strategy entirely. On the contrary, it compels players to reassess their resource management tactics throughout the game, making each decision count even more.

In this game, the toughest part is choosing which weapons and accessories to hold onto or sell, as there’s no option to save valuable items for future use. This decision adds a strategic layer and demands a good grasp of the game’s advancement to make optimal use of what Leon can carry effectively.

6 No Crafting Run Or No Ammo Pickups Run

Refrain From Crafting Ammo, Or Rely Only On Ammo Crafting Without Pickups

In a “No Crafting, No Ammo” scenario, there are two distinct difficulty modes to choose from:

Both runs introduce a level of unpredictability, as players must rely on luck to get the right drops. While the random nature of resource drops can make these runs tricky, they offer a fresh and exciting way to tackle the game.

7 No Charm Run

Refrain From Using Any Attache Case Charms With Bonuses

In the Resident Evil 4 Remake, one intriguing difficulty is the Charmless mode, where players cannot use any extra charms in their attaché case. Although these charms offer useful perks, doing without them entirely can significantly increase the challenge, particularly on harder settings.

This individual run may not significantly alter the game on its own, but it harmonizes effectively with nearly any additional custom challenge. As a result, players can devise their unique set of rules and amplify Leon’s adventure with added difficulty. For instance, it complements the No Ammo Pickups run exceptionally well, which limits players to utilizing only the ammo they can craft themselves. Many charms boost ammo production through crafting in this scenario.

8 Demolisher Run

Rely Only On Explosives To Kill Enemies

For a tougher test, players can try the Run with Only Explosives, in which they aim to vanquish adversaries exclusively by employing explosives – except for the Indestructible Rocket Launcher. This requires them to rely entirely on diverse grenade types and the Bolt Thrower’s detachable mines to inflict damage.

In this run, the most challenging part is ensuring you don’t accidentally hit Leon’s teammates Ashley or Luis with friendly fire, particularly during intense battles with many enemies. To provide more gameplay options, players can opt to let knives be used, although this is completely up to them.

9 No Kill Run

Refrain From Killing Any Enemies Other Than Progression Blockers

As a devoted fan, I’ve got to say, tackling the No Kill Run in the Resident Evil 4 Remake isn’t for the casual player. This tough-as-nails challenge requires me to steer clear of offing any enemies unless they’re absolutely essential for progress. With so many optional foes scattered all over the game, it’s a test of patience and precision that only the brave can conquer.

To excel in this game, it’s crucial that players have a thorough understanding of each chapter, allowing them to strategize their actions wisely and identify the specific adversaries they need to tackle to advance. Prepare for challenging, high-stress sequences filled with escapes and dodging enemies. It’s advisable to prioritize exchanging ammunition for health supplies or armor to boost your chances of survival in this grueling playthrough.

10 Perfect Accuracy Run

Achieve 100% Accuracy Throughout the Entire Playthrough

For those who strive for unparalleled precision, the Perfect Accuracy mode in this game demands players to finish without a single missed shot throughout the entire gaming session. This task calls for perseverance, lightning-fast reactions, and exceptional aim, thereby making it one of the most challenging yet satisfying endeavors.

During this gameplay session, the goal is for players to embody Leon S. Kennedy’s professional demeanor, firing their weapon only when completely certain of hitting the target. This challenge truly assesses one’s ability, demanding a blend of accuracy and self-restraint.

2024-10-14 00:14