The Secret Drug That Finally Killed Muzan in Demon Slayer Revealed

Summary

The Anti-Kibutsuji drug was pivotal in defeating Muzan by converting him into a human, rapidly aging him, and breaking him down at a cellular level.
The drug weakened Muzan substantially, preventing his escape from battle and stopping his regenerative abilities.
Without Tamayo’s sacrifice to inject the drug and Shinobu’s expertise, Muzan would have easily won the final battle.

In the nail-biting climax of “Demon Slayer: Kimetsu No Yaiba,” I found myself squarely in the midst of an epic showdown against Muzan Kibutsuji, the deadliest demon ever known. This relentless beast had already claimed countless lives, even leaving the mightiest Hashira powerless in its wake.

While Muzan continued his rampage against the corps, unaware was he that a potent weapon had been crafted with the sole purpose of vanquishing him. This formidable tool turned out to be none less than the Anti-Kibutsuji serum, meticulously developed by the combined skills of Tamayo, Yushiro, and Shinobu. In due course, this potent concoction proved instrumental in finally putting an end to Muzan’s reign.

The Four-Effect Drug Preparation For The Battle Against Muzan

How Did The Anti-Kibutsuji Drug Work?

Even though Shinobu harbored intense dislike towards demons, she set her animosity aside and collaborated with Tamayo, understanding that this was the sole means to thwart Muzan. Tamayo had extensive knowledge about Muzan, being well-versed in his powers and vulnerabilities.

We don’t have the strength to fight Muzan head-on, so we will take away his power instead – Tomayo

Embracing my passion for this extraordinary endeavor, I found myself standing shoulder-to-shoulder with the brilliant Shinobu, whose deep understanding of Wisteria Poison, a formidable weapon against demons, played a pivotal role. Together, we crafted the potent Anti Kibutsuji elixir, tipping the scales decisively in our favor during the fierce battle. Designed to wield four significant impacts on Muzan, this miraculous concoction was nothing short of a game-changer.

Converting Muzan Into A Human

Initially, the medication caused Muzan to transform from a demon back into a human. This was quite daring since transforming into a demon is considered irreversible, and the only escape from this curse is death. Yet, Tamayo had spent years searching for a potential remedy to lift the curse and enable a demon to regain their humanity again.

In the aftermath of each fight Nezuko was involved in, Tamayo had been investigating her blood. Unfortunately, the initial effect of the drug didn’t take hold, which meant Muzan remained a demon and continued to pose a significant threat. Despite the drug weakening him, Tamayo and Shinobu understood they needed something more potent to vanquish Muzan. To guarantee his defeat, they crafted the drug with three extra properties.

Rapid Aging

The drug’s secondary action hindered Muzan’s rapid healing ability. His power was such that he could swiftly recuperate from the most lethal blows and in a blink of an eye, even if he were torn into the tiniest fragments, he would regrow almost instantly.

The medication sped up Muzan’s aging process, equivalent to around 50 years per minute, a rate that would gradually wear down his body over an extended period. This rapid aging made him extremely vulnerable, and within roughly 5 hours of ingesting the drug, Muzan began to age rapidly. He progressively lost his physical power and endurance, and his attacks significantly weakened as a result.

Stopping Muzan From Escaping Battle

Tamayo understood that, once Muzan was on the brink of losing, he’d fragment himself into smaller pieces to flee the battlefield. After reaching a secure location, Muzan would then rejuvenate himself.

I don’t have to be more powerful than you for me to end you. Instead, I will weaken you. Just as you would go to any length to survive, so will we go to any length to eliminate you.

In other words, the third outcome was to keep Muzan from dividing himself and slipping away, allowing the corps to finally defeat him completely.

Breaking Muzan Down At The Cellular Level

In the end, the Anti-Kibutsuji drug’s deadliest consequence was to disintegrate Muzan at a cellular level, ultimately leading to his demise. This destructive impact gradually caused his cells to perish, effectively halting his regenerative and healing powers.

As the drug fully consumed Muzan’s physical form, the Demon King began to disintegrate. Despite his attempts to sustain life by devouring the corps members, it was all for naught as the drug had already accomplished its purpose.

The Drug’s Role In Defeating Muzan

This medication played a crucial role in the Demon Slayers’ ability to finally vanquish Muzan permanently. In its absence, Muzan would have continued fighting at his maximum capacity, likely resulting in the death of every member of the Demon Slayer Corps as depicted in the series.

Without Tamayo’s selfless act of administering the drug and Shinobu’s assistance in enhancing its potency, Muzan, the demon king, would have effortlessly triumphed.

2025-03-14 04:08